This study validates the performance of a SNP-based mmPCR assay to detect the dd-cfDNA fraction with improved precision over currently available tests, regardless of donor-recipient relationships...

This study validates the use of dd-cfDNA in the blood as an accurate marker of kidney

In summary, we have developed and analytically validated a clinical-grade NGS test to measure the fraction of dd-cfDNA in plasma of solid organ transplant patients. This test is applicable to single-organ donor-recipient pairs and does not depend on separate determination of either donor or recipient genotypes...